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	Provedor de dados BJMBR (2) BJPS (1) Autor Delgado,Gabriela (1) Ding,Y. (1) Herrero,C. (1) Lu,J. (1) Mariño,Angélica (1) Plaza,David (1) Pérez-Simón,J.A. (1) Yi,X. (1) Zheng,J. (1) Mais... Palavra-chave B-lymphocytes (3) Allogeneic transplanta (1) B-lymphocyte subsets (1) BALB/c ICR (1) Blastogenesis (1) Cyclosporine A/adverse effects (1) Cyclosporine A/immunomodulatory effects (1) Dendritic cells (1) Flow cytometry (1) Graft-versus-host disease (1) Immunotoxicity (1) Mesenchymal stem cells (1) Psoriasis (1) Psoriasis Area Severity Index (PASI) (1) T-lymphocytes (1) Mais... Tipo do documento Info:eu-repo/semantics/article (3) Ano 2016 (1) 2011 (1) 2010 (1) País Brazil (3) Idioma Inglês (3)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 3 Primeira ... 1 ... Última CD19+ B cell subsets in the peripheral blood and skin lesions of psoriasis patients and their correlations with disease severity BJMBR Lu,J.; Ding,Y.; Yi,X.; Zheng,J.. T lymphocytes are important in the pathogenesis of psoriasis, and increasing evidence indicates that B cells also play an important role. The mechanisms of action, however, remain unclear. We evaluated the ratios of CD19+ B cells in peripheral blood mononuclear cells (PBMCs) from 157 patients with psoriasis (65 patients with psoriasis vulgaris, 32 patients with erythrodermic psoriasis, 30 patients with arthropathic psoriasis, and 30 patients with pustular psoriasis) and 35 healthy controls (HCs). Ratios of CD19+ B cells in skin lesions were compared with non-lesions in 7 erythrodermic psoriasis patients. The Psoriasis Area Severity Index (PASI) was used to measure disease severity. CD19+ B cell ratios in PBMCs from psoriasis vulgaris (at both the active... Tipo: Info:eu-repo/semantics/article Palavras-chave: Psoriasis; B-lymphocytes; B-lymphocyte subsets; Psoriasis Area Severity Index (PASI); Flow cytometry. Ano: 2016 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2016000900706 Immunomodulatory effect of mesenchymal stem cells BJMBR Herrero,C.; Pérez-Simón,J.A.. Mesenchymal stem cells (MSC) are multipotential nonhematopoietic progenitor cells capable of differentiating into multiple mesenchymal tissues. MSC are able to reconstitute the functional human hematopoietic microenvironment and promote engraftment of hematopoietic stem cells. MSC constitutively express low levels of major histocompatibility complex-I molecules and do not express costimulatory molecules such as CD80, CD86 or CD40, thus lacking immunogenicity. Furthermore, they are able to suppress T- and B-lymphocyte activation and proliferation and may also affect dendritic cell maturation. Based on these properties, MSC are being used in regenerative medicine and also for the treatment of autoimmune diseases and graft-versus-host disease. On the other... Tipo: Info:eu-repo/semantics/article Palavras-chave: Mesenchymal stem cells; T-lymphocytes; B-lymphocytes; Dendritic cells; Graft-versus-host disease; Allogeneic transplanta. Ano: 2010 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2010000500002 Preliminary study to characterize differences in potential immunomodulatory effects of cyclosporine A using BALB/c and ICR mouse splenocytes BJPS Mariño,Angélica; Plaza,David; Delgado,Gabriela. Cyclosporine A (CsA) is widely used as an immunosuppressant for the treatment of autoimmune diseases and immune regulation in transplant patients. Due to its wide applicability, studies of unwanted side effects of CsA are imperative. It has been found that not all patients treated with CsA display the same types/patterns of adverse effects. To ascertain the bases for these differential responses, potential differing effects of CsA on B-lymphocytes were analyzed. This entailed an assessment of changes in CsA viability and mitotic activity within splenocyte populations from BALB/c and ICR mice. These particular strains were examined because: (1) in each of them, previously have been shown that differed in the respond to biological response modifiers, such as... Tipo: Info:eu-repo/semantics/article Palavras-chave: Immunotoxicity; Cyclosporine A/immunomodulatory effects; Cyclosporine A/adverse effects; B-lymphocytes; BALB/c ICR; Blastogenesis. Ano: 2011 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502011000100022 Registros recuperados: 3 Primeira ... 1 ... Última

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